Sheldon Lee Glashow was born in Brooklyn, New York, in 1933. He received his B.S. in physics from Ohio State University in 1955 and his Ph.D. in physics from Harvard University in 1960, working under the supervision of Nobel laureate Abdus Salam
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After three years at Cornell University as a postdoctoral fellow, he became professor of physics at Harvard in 1966, where he continued to work on particle physics and also served as Department chairman (1982–1995), Dean of Science (1982–1985), and Vice President for Academic Affairs (1985–1990). He was elected to the National Academy of Sciences in 1974 and to the American Academy of Arts and Sciences in 1981. He was awarded the Enrico Fermi Award by the American Physical Society for his development of theories of elementary particle physics, and shared the 1997 Nobel Prize for Physics with Murray Gell-Mann "for their discovery of quarks."